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Tissue Kallikrein Protects Against Pressure Overload-Induced Cardiac Hypertrophy through Kinin B2 Receptor and Glycogen Synthase Kinase-3β Activation
OBJECTIVE: We assessed the role of glycogen synthase kinase-3β(GSK-3β) and kinin B2 receptor in mediating tissue kallikrein’s protective effects against cardiac hypertrophy. METHODS: We investigated the effect and mechanisms of tissue kallikrein using hypertrophic animal models of rats as well as mi...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847347/ https://ncbi.nlm.nih.gov/pubmed/17137568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cardiores.2006.10.014 |
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