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A family of human receptors structurally related to Drosophila Toll

The discovery of sequence homology between the cytoplasmic domains of Drosophila Toll and human interleukin 1 receptors has sown the conviction that both molecules trigger related signaling pathways tied to the nuclear translocation of Rel-type transcription factors. This conserved signaling scheme...

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Autors principals: Rock, Fernando L., Hardiman, Gary, Timans, Jackie C., Kastelein, Robert A., Bazan, J. Fernando
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18464/
https://ncbi.nlm.nih.gov/pubmed/9435236
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