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Multiple-dose pharmacokinetics of the monobactam azthreonam (SQ 26,776) in healthy subjects.

Azthreonam, a monocyclic beta-lactam highly active against aerobic gram-negative bacteria in vitro, was administered to four groups of nine healthy male volunteers in the following four regimens: 500 mg intravenously (i.v.) over 2 min every 8 h, 1,000 mg i.v. over 2 min every 8 h, 500 mg intramuscul...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Swabb, E A, Sugerman, A A, McKinstry, D N
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1983
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184629/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6681947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.1.125
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