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Binding of monobactams to penicillin-binding proteins of Escherichia coli and Staphylococcus aureus: relation to antibacterial activity.

A series of novel monocyclic beta-lactam antibiotics having side chains related to penicillin, piperacillin, azlocillin, and cefotaxime were examined with respect to binding to essential penicillin-binding proteins (PBPs) in Escherichia coli and Staphylococcus aureus. In the penicillin series, there...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Georgopapadakou, N H, Smith, S A, Cimarusti, C M, Sykes, R B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1983
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184624/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6338822/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.1.98
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