Aminoglycoside accumulation kinetics in rat renal parenchyma.

To test the hypotheses that the renal parenchymal accumulation kinetics of aminoglycosides can predict nephrotoxicity, we measured renal parenchymal concentrations in rats receiving gentamicin and tobramycin. In addition to comparing the drugs as single daily injections, we also examined the effect...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Aronoff, G R, Pottratz, S T, Brier, M E, Walker, N E, Fineberg, N S, Glant, M D, Luft, F C
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1983
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6830211/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.1.74
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