Mechanism of renal excretion of AM-715, a new quinolonecarboxylic acid derivative, in rabbits, dogs, and humans.

The mechanisms of the renal excretion of AM-715, a synthetic antimicrobial agent, were studied in rabbits, dogs, and humans. In both rabbits and humans, AM-715 clearance was greater than creatinine clearance and was profoundly decreased by the administration of probenecid. Thus, in these subjects, A...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Shimada, J, Yamaji, T, Ueda, Y, Uchida, H, Kusajima, H, Irikura, T
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1983
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC184605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6219615/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.23.1.1
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