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Endogenous activation of metabotropic glutamate receptors in neocortical development causes neuronal calcium oscillations

Oscillations in intracellular free calcium concentration ([Ca(2+)](i)) occur spontaneously in immature neurons of the developing cerebral cortex. Here, we show that developing murine cortical neurons exhibit calcium oscillations in response to direct activation of the mGluR5 subtype of the group I m...

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Detalhes bibliográficos
Main Authors: Flint, Alexander C., Dammerman, Ryan S., Kriegstein, Arnold R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18426/
https://ncbi.nlm.nih.gov/pubmed/10518590
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