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Underdeveloped uterus and reduced estrogen responsiveness in mice with disruption of the estrogen-responsive finger protein gene, which is a direct target of estrogen receptor α

The biological roles of estrogen-responsive finger protein (efp) in vivo were evaluated in mice carrying a loss-of-function mutation in efp by gene-targeted mutagenesis. Although efp homozygous mice were viable and fertile in both sexes, the uterus that expressed abundant estrogen receptor α exhibit...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Orimo, Akira, Inoue, Satoshi, Minowa, Osamu, Tominaga, Nobuko, Tomioka, Yasuhiro, Sato, Miyuki, Kuno, Junko, Hiroi, Hisahiko, Shimizu, Yoshihiko, Suzuki, Masami, Noda, Tetsuo, Muramatsu, Masami
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18406/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518570/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.12027
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