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Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility

Thymocyte development is reported to be inhibited by pregnancy, although the impact of this effect on fertility is unknown. We demonstrate, using progesterone receptor null mutant mice, that the inhibitory effects of pregnancy hormones on T cell development require the presence of functional progest...

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Detalles Bibliográficos
Main Authors: Tibbetts, Todd A., DeMayo, Franco, Rich, Susan, Conneely, Orla M., O’Malley, Bert W.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC18405/
https://ncbi.nlm.nih.gov/pubmed/10518569
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