Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility

Thymocyte development is reported to be inhibited by pregnancy, although the impact of this effect on fertility is unknown. We demonstrate, using progesterone receptor null mutant mice, that the inhibitory effects of pregnancy hormones on T cell development require the presence of functional progest...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Tibbetts, Todd A., DeMayo, Franco, Rich, Susan, Conneely, Orla M., O’Malley, Bert W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.12021
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