Point Mutations in the Stem Region and the Fourth AAA Domain of Cytoplasmic Dynein Heavy Chain Partially Suppress the Phenotype of NUDF/LIS1 Loss in Aspergillus nidulans

Cytoplasmic dynein performs multiple cellular tasks but its regulation remains unclear. The dynein heavy chain has a N-terminal stem that binds to other subunits and a C-terminal motor unit that contains six AAA (ATPase associated with cellular activities) domains and a microtubule-binding site loca...

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Main Authors: Zhuang, Lei, Zhang, Jun, Xiang, Xin
Formato: Artigo
Idioma:Inglês
Publicado: Copyright © 2007 by the Genetics Society of America 2007
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Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1840067/
https://ncbi.nlm.nih.gov/pubmed/17237507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.069013
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