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Conserved signal peptide of Notch3 inhibits interaction with proteasome

The Notch3 N-terminal sequence is conserved across several mammalian species but diverges from the three other Notch proteins. We determined the significance of the N-terminal sequence using deletion mutants. The first 39 amino acids are required for Notch3 receptor expression, processing and functi...

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Autors principals: Zhang, Yanmei, Jia, Lijun, Lee, Soo Jung, Wang, Michael M.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839862/
https://ncbi.nlm.nih.gov/pubmed/17292860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.01.151
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