CD40Ig treatment results in allograft acceptance mediated by CD8(+)CD45RC(low) T cells, IFN-γ, and indoleamine 2,3-dioxygenase

Treatment with CD40Ig results in indefinite allograft survival in a complete MHC-mismatched heart allograft model in the rat. Here we show that serial second, third, and fourth adoptive transfers of total splenocytes from CD40Ig-treated recipients into secondary recipients led to indefinite donor-sp...

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Detalhes bibliográficos
Main Authors: Guillonneau, Carole, Hill, Marcelo, Hubert, François-Xavier, Chiffoleau, Elise, Hervé, Caroline, Li, Xian-Liang, Heslan, Michèle, Usal, Claire, Tesson, Laurent, Ménoret, Séverine, Saoudi, Abdelhadi, Le Mauff, Brigitte, Josien, Régis, Cuturi, Maria Cristina, Anegon, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839240/
https://ncbi.nlm.nih.gov/pubmed/17404623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28801
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