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Bacterial Ligands Generated in a Phagosome Are Targets of the Cytosolic Innate Immune System

Macrophages are permissive hosts to intracellular pathogens, but upon activation become microbiocidal effectors of innate and cell-mediated immunity. How the fate of internalized microorganisms is monitored by macrophages, and how that information is integrated to stimulate specific immune responses...

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Autores principales: Herskovits, Anat A, Auerbuch, Victoria, Portnoy, Daniel A
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839167/
https://ncbi.nlm.nih.gov/pubmed/17397264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030051
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