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Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development
Ewing sarcoma gene EWS encodes a putative RNA-binding protein with proposed roles in transcription and splicing, but its physiological role in vivo remains undefined. Here, we have generated Ews-deficient mice and demonstrated that EWS is required for the completion of B cell development and meiosis...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838927/ https://ncbi.nlm.nih.gov/pubmed/17415412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31222 |
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