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Clinical implications and utility of field cancerization

Cancer begins with multiple cumulative epigenetic and genetic alterations that sequencially transform a cell, or a group of cells in a particular organ. The early genetic events might lead to clonal expansion of pre-neoplastic daughter cells in a particular tumor field. Subsequent genomic changes in...

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Detalhes bibliográficos
Main Authors: Dakubo, Gabriel D, Jakupciak, John P, Birch-Machin, Mark A, Parr, Ryan L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838897/
https://ncbi.nlm.nih.gov/pubmed/17362521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-7-2
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