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Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics
The genetic factors contributing to the complex disorder of myocardial calcification are largely unknown. Using a mouse model, we fine-mapped the major locus (Dyscalc1) contributing to the dystrophic cardiac calcification (DCC) to an 840-kb interval containing 38 genes. We then identified the causal...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2007
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838635/ https://ncbi.nlm.nih.gov/pubmed/17360558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607620104 |
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