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Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics
The genetic factors contributing to the complex disorder of myocardial calcification are largely unknown. Using a mouse model, we fine-mapped the major locus (Dyscalc1) contributing to the dystrophic cardiac calcification (DCC) to an 840-kb interval containing 38 genes. We then identified the causal...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838635/ https://ncbi.nlm.nih.gov/pubmed/17360558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607620104 |
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