Genomic identification and in vitro reconstitution of a complete biosynthetic pathway for the osmolyte di-myo-inositol-phosphate

Di-myo-inositol 1,1′-phosphate (DIP) is a major osmoprotecting metabolite in a number of hyperthermophilic species of archaea and bacteria. Although the DIP biosynthesis pathway was previously proposed, genes encoding only two of the four required enzymes, inositol-1-phosphate synthase and inositol...

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Bibliographische Detailangaben
Hauptverfasser: Rodionov, Dmitry A., Kurnasov, Oleg V., Stec, Boguslaw, Wang, Yan, Roberts, Mary F., Osterman, Andrei L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838593/
https://ncbi.nlm.nih.gov/pubmed/17360515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609279104
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