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HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53

In response to DNA damage, p53 undergoes post-translational modifications (including acetylation) that are critical for its transcriptional activity. However, the mechanism by which p53 acetylation is regulated is still unclear. Here, we describe an essential role for HLA-B-associated transcript 3 (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sasaki, Toru, Gan, Eugene C., Wakeham, Andrew, Kornbluth, Sally, Mak, Tak W., Okada, Hitoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838535/
https://ncbi.nlm.nih.gov/pubmed/17403783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1534107
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