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Molecular Mechanism of Membrane Docking by the Vam7p PX Domain

The Vam7p t-SNARE is an essential component of the vacuole fusion machinery that mediates membrane trafficking and protein sorting in yeast. Vam7p is recruited to vacuoles by its N-terminal PX domain that specifically recognizes PtdIns(3)P in the bilayers, however the precise mechanism of membrane a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Stephanie A., Kovacs, James, Stahelin, Robert V., Cheever, Matthew L., Overduin, Michael, Gangi Setty, Thanuja, Burd, Christopher G., Cho, Wonhwa, Kutateladze, Tatiana G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838524/
https://ncbi.nlm.nih.gov/pubmed/16984909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M608610200
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