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Effect of allopurinol on Trypanosoma cruzi: metabolism and biological activity in intracellular and bloodstream forms.

Allopurinol (4-hydroxypyrazolo [3,4-d]pyrimidine) is an effective agent in vitro against Trypanosoma cruzi. The important forms of this parasite, with respect to the pathogenesis of Chagas' disease in man, are the bloodstream (trypomastigote) and the intracellular forms. Experiments with radiol...

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Dettagli Bibliografici
Autori principali: Berens, R L, Marr, J J, Steele da Cruz, F S, Nelson, D J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1982
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC183810/
https://ncbi.nlm.nih.gov/pubmed/6817705
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