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Pharmacokinetics and cerebrospinal fluid bactericidal activity of ceftriaxone in the treatment of pediatric patients with bacterial meningitis.

Single-dose pharmacokinetics of ceftriaxone were determined in 19 patients with proven bacterial meningitis. The dosage was 50 mg of ceftriaxone per kg. The plasma concentration time curve declined in a biexponential manner. The mean peak plasma concentration was 207 micrograms/ml, and the eliminati...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Del Rio, M, McCracken, G H, Nelson, J D, Chrane, D, Shelton, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183803/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6295262/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.4.622
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