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Antibacterial activity and mechanism of action of phosphonopeptides based on aminomethylphosphonic acid.

Phosphonopeptides based on aminomethylphosphonic acid as the C-terminal residue linked to L-amino acids possessed antibacterial activity in vitro and in vivo. Analogs in this series were generally less potent than corresponding compounds based on L-1-aminoethylphosphonic acid such as alafosfalin (L-...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Atherton, F R, Hall, M J, Hassall, C H, Lambert, R W, Lloyd, W J, Ringrose, P S, Westmacott, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1982
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6758686/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.4.571
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