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The combined absence of the transcription factors Rel and RelA leads to multiple hemopoietic cell defects

Individual Rel/NF-κB transcription factors, although dispensable for the development and maturation of most hemopoietic cells, are critical regulators of normal immune function. Redundancy among these proteins prompted us to examine the role of Rel and RelA in hemopoiesis by using mice that lack bot...

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Detalles Bibliográficos
Main Authors: Grossmann, Mathis, Metcalf, Donald, Merryfull, Julie, Beg, Amer, Baltimore, David, Gerondakis, Steve
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC18375/
https://ncbi.nlm.nih.gov/pubmed/10518539
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