Role of the integrin-associated protein CD9 in binding between sperm ADAM 2 and the egg integrin α6β1: Implications for murine fertilization

CD9 is a tetraspan protein that associates with several β1 integrins, including α6β1. Because α6β1 is present on murine eggs and interacts with the sperm-surface glycoprotein ADAM 2 (fertilin β), we first asked whether CD9 is present on murine eggs and whether it functions in sperm–egg binding and f...

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Detalhes bibliográficos
Main Authors: Chen, Michellee S., Tung, Kenneth S. K., Coonrod, Scott A., Takahashi, Yuji, Bigler, Dora, Chang, Alice, Yamashita, Yoshio, Kincade, Paul W., Herr, John C., White, Judith M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18372/
https://ncbi.nlm.nih.gov/pubmed/10518536
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