Island-wide diversity in single nucleotide polymorphisms of the Plasmodium vivax dihydrofolate reductase and dihydropteroate synthetase genes in Sri Lanka

BACKGROUND: Single nucleotide polymorphisms (SNPs) in the Plasmodium vivax dihydrofolate reductase (Pfdhfr) and dihydropteroate synthetase (Pvdhps) genes cause parasite resistance to the antifolate drug combination, sulphadoxine/pyrimethamine (SP). Monitoring these SNPs provide insights into the lev...

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Main Authors: Schousboe, Mette L, Rajakaruna, Rupika S, Salanti, Ali, Hapuarachchi, Hapuarachchige C, Galappaththy, Gawrie NL, Bygbjerg, Ib C, Amerasinghe, Priyanie H, Konradsen, Flemming, Alifrangis, Michael
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831779/
https://ncbi.nlm.nih.gov/pubmed/17349045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-6-28
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