Association between CFL1 gene polymorphisms and spina bifida risk in a California population

BACKGROUND: CFL1 encodes human non-muscle cofilin (n-cofilin), which is an actin-depolymerizing factor and is essential in cytokinesis, endocytosis, and in the development of all embryonic tissues. Cfl1 knockout mice exhibit failure of neural tube closure at E10.5 and die in utero. We hypothesized t...

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Hlavní autoři: Zhu, Huiping, Enaw, James O Ebot, Ma, Chen, Shaw, Gary M, Lammer, Edward J, Finnell, Richard H
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831766/
https://ncbi.nlm.nih.gov/pubmed/17352815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-12
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