Association between CFL1 gene polymorphisms and spina bifida risk in a California population

BACKGROUND: CFL1 encodes human non-muscle cofilin (n-cofilin), which is an actin-depolymerizing factor and is essential in cytokinesis, endocytosis, and in the development of all embryonic tissues. Cfl1 knockout mice exhibit failure of neural tube closure at E10.5 and die in utero. We hypothesized t...

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Bibliographic Details
Main Authors: Zhu, Huiping, Enaw, James O Ebot, Ma, Chen, Shaw, Gary M, Lammer, Edward J, Finnell, Richard H
Format: Artigo
Language:Inglês
Published: BioMed Central 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831766/
https://ncbi.nlm.nih.gov/pubmed/17352815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-12
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