GLUCOSE- AND TIME-DEPENDENCE OF ISLET AMYLOID FORMATION IN VITRO

Islet amyloid contributes to the loss of β-cell mass in type 2 diabetes. To examine the roles of glucose and time on amyloid formation, we developed a rapid in vitro model using isolated islets from human islet amyloid polypeptide (hIAPP) transgenic mice. Islets from hIAPP transgenic and non-transge...

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Huvudupphovsmän: Zraika, Sakeneh, Hull, Rebecca L., Udayasankar, Jayalakshmi, Utzschneider, Kristina M., Tong, Jenny, Gerchman, Fernando, Kahn, Steven E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1831460/
https://ncbi.nlm.nih.gov/pubmed/17222388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.12.187
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