Stabilization of botulinum toxin type A during lyophilization.
Botulinum toxin for medical use is diluted to very low concentrations (nanograms per milliliter); when it is preserved by lyophilization, considerable loss of activity can occur. In the present study, conditions that gave > 90% recovery of the toxicity after lyophilization of solutions containing 20...
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| Published in: | Appl Environ Microbiol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1992
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1444378/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.58.10.3426-3428.1992 |
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