Stabilization of botulinum toxin type A during lyophilization.

Botulinum toxin for medical use is diluted to very low concentrations (nanograms per milliliter); when it is preserved by lyophilization, considerable loss of activity can occur. In the present study, conditions that gave > 90% recovery of the toxicity after lyophilization of solutions containing 20...

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Detalhes bibliográficos

Publicado no:	Appl Environ Microbiol
Principais autores:	Goodnough, M C, Johnson, E A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC183118/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1444378/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.58.10.3426-3428.1992
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