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Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties

Hematopoietic stem cells (HSCs) execute self-renewal divisions throughout fetal and adult life, although some of their properties do alter. Here we analyzed the magnitude and timing of changes in the self-renewal properties and differentiated cell outputs of transplanted HSCs obtained from different...

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Detalhes bibliográficos
Main Authors: Bowie, Michelle B., Kent, David G., Dykstra, Brad, McKnight, Kristen D., McCaffrey, Lindsay, Hoodless, Pamela A., Eaves, Connie J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829493/
https://ncbi.nlm.nih.gov/pubmed/17379664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700460104
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