EVIDENCE OF EXTRA-TELOMERIC EFFECTS OF hTERT AND ITS REGULATION INVOLVING A FEEDBACK LOOP(*)

The human telomerase reverse transcriptase (hTERT) is the catalytic subunit of the enzyme telomerase which is responsible for telomeric maintenance and extension. Using RNA interference to knock down hTERT mRNA expression, we provide evidence that hTERT exerts extra-telomeric effects on the cell cyc...

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Detaylı Bibliyografya
Asıl Yazarlar: Lai, Serene R., Cunningham, Amanda P., Huynh, Vu Q., Andrews, Lucy G., Tollefsbol, Trygve O.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829489/
https://ncbi.nlm.nih.gov/pubmed/17134697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2006.10.014
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