Novel Roles of Local Insulin-Like Growth Factor-1 Activation in Gastric Ulcer Healing : Promotes Actin Polymerization, Cell Proliferation, Re-Epithelialization, and Induces Cyclooxygenase-2 in a Phosphatidylinositol 3-Kinase-Dependent Manner

The precise role of insulin-like growth factor (IGF)-1 in gastric ulcer healing is unknown. In experimental rat gastric ulcers, we examined expression of IGF-1 mRNA and protein by reverse transcriptase-polymerase chain reaction or enzyme-linked immunosorbent assay and immunostaining, respectively. I...

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Detalhes bibliográficos
Principais autores: Nguyen, Tom, Chai, Jianyuan, Li, Aihua, Akahoshi, Tomohiko, Tanigawa, Tetsuya, Tarnawski, Andrzej S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829456/
https://ncbi.nlm.nih.gov/pubmed/17392162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060745
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