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Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling
Mycobacterium tuberculosis synthesizes specific polyketide lipids that interact with the host and are required for virulence. Using a mass spectrometric approach to simultaneously monitor hundreds of lipids, we discovered that the size and abundance of two lipid virulence factors, phthiocerol dimyco...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1829275/ https://ncbi.nlm.nih.gov/pubmed/17360366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610634104 |
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