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Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling

Mycobacterium tuberculosis synthesizes specific polyketide lipids that interact with the host and are required for virulence. Using a mass spectrometric approach to simultaneously monitor hundreds of lipids, we discovered that the size and abundance of two lipid virulence factors, phthiocerol dimyco...

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Bibliografiska uppgifter
Huvudupphovsmän: Jain, Madhulika, Petzold, Christopher J., Schelle, Michael W., Leavell, Michael D., Mougous, Joseph D., Bertozzi, Carolyn R., Leary, Julie A., Cox, Jeffery S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829275/
https://ncbi.nlm.nih.gov/pubmed/17360366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610634104
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