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The role of cells refractory to productive infection in acute hepatitis B viral dynamics

During acute hepatitis B virus (HBV) infection viral loads reach high levels (≈10(10) HBV DNA per ml), and nearly every hepatocyte becomes infected. Nonetheless, ≈85–95% of infected adults clear the infection. Although the immune response has been implicated in mediating clearance, the precise mecha...

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Библиографические подробности
Главные авторы: Ciupe, Stanca M., Ribeiro, Ruy M., Nelson, Patrick W., Dusheiko, Geoffrey, Perelson, Alan S.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829262/
https://ncbi.nlm.nih.gov/pubmed/17360406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603626104
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