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S-adenosylmethionine directly inhibits binding of 30S ribosomal subunits to the S(MK) box translational riboswitch RNA

The S(MK) box is a conserved riboswitch motif found in the 5′ untranslated region of metK genes [encoding S-adenosylmethionine (SAM) synthetase] in lactic acid bacteria, including Enterococcus, Streptococcus, and Lactococcus sp. Previous studies showed that this RNA element binds SAM in vitro, and S...

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Autors principals: Fuchs, Ryan T., Grundy, Frank J., Henkin, Tina M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829232/
https://ncbi.nlm.nih.gov/pubmed/17360376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609956104
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