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Morphine Reciprocally Regulates IL-10 and IL-12 Production by Monocyte-Derived Human Dendritic Cells and Enhances T Cell Activation

We evaluated the effect of morphine on human dendritic cells (DCs). Interestingly, immature DCs were found to express all 3 (μ, κ, δ) opioid receptors on the cell surface. Chronic morphine treatment (10(−8) to 10(−12) M) during the development of DCs from monocytes augmented LPS-induced upregulation...

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Detalhes bibliográficos
Main Authors: Messmer, Davorka, Hatsukari, Ikusuke, Hitosugi, Naoko, Schmidt-Wolf, Ingo GH, Singhal, Pravin C
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829197/
https://ncbi.nlm.nih.gov/pubmed/17380193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2006-00043.Messmer
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