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Defibrinated bovine plasma inhibits retroviral transcription by blocking p52 activation of the NFκB element in the long terminal repeat

Bovine leukemia virus (BLV) induces a persistent but latent infection in cattle. Viral latency is invoked by a protein known as plasma blocking factor (PBF) that is found in both bovine and human plasma. We report here on pathways that mediate latency in the presence of PBF. Reporter-gene constructs...

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Detalhes bibliográficos
Main Authors: van den Heuvel, Marianne J., Copeland, Karen F., Cates, Elizabeth C., Jefferson, Barbara J., Jacobs, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Veterinary Medical Association 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829189/
https://ncbi.nlm.nih.gov/pubmed/17479775
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