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Rapid Detection of Point Mutations Conferring Resistance to Fluoroquinolone in gyrA of Helicobacter pylori by Allele-Specific PCR

Helicobacter pylori strains with reduced susceptibility to fluoroquinolones have a mutation at either codon 87 Asn or 91 Asp of the gyrA gene. A rapid test based on an allele-specific PCR (AS-PCR) was designed to detect the gyrA mutations. Clinical H. pylori isolates were obtained from the stomachs...

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Autori principali: Nishizawa, Toshihiro, Suzuki, Hidekazu, Umezawa, Ayako, Muraoka, Hiroe, Iwasaki, Eisuke, Masaoka, Tatsuhiro, Kobayashi, Intetsu, Hibi, Toshifumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829027/
https://ncbi.nlm.nih.gov/pubmed/17122023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01997-06
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