Role of Large Sequence Polymorphisms (LSPs) in Generating Genomic Diversity among Clinical Isolates of Mycobacterium tuberculosis and the Utility of LSPs in Phylogenetic Analysis

Mycobacterium tuberculosis strains contain different genomic insertions or deletions called large sequence polymorphisms (LSPs). Distinguishing between LSPs that occur one time versus ones that occur repeatedly in a genomic region may provide insights into the biological roles of LSPs and identify u...

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Autors principals: Alland, David, Lacher, David W., Hazbón, Manzour Hernando, Motiwala, Alifiya S., Qi, Weihong, Fleischmann, Robert D., Whittam, Thomas S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Mycobacteriology and Aerobic Actinomycetes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828963/
https://ncbi.nlm.nih.gov/pubmed/17079498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02483-05
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