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Calcium regulates tertiary structure and enzymatic activity of human endometase/matrilysin-2 and its role in promoting human breast cancer cell invasion

Human MMP-26 (matrix metalloproteinase-26) (also known as endometase or matrilysin-2) is a putative biomarker for human carcinomas of breast, prostate and other cancers of epithelial origin. Calcium modulates protein structure and function and may act as a molecular signal or switch in cells. The re...

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Библиографические подробности
Главные авторы: Lee, Seakwoo, Park, Hyun I., Sang, Qing-Xiang Amy
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828896/
https://ncbi.nlm.nih.gov/pubmed/17176253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061390
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