Recombinant Protein-Based Assays for Detection of Antibodies to Severe Acute Respiratory Syndrome Coronavirus Spike and Nucleocapsid Proteins

Recombinant severe acute respiratory syndrome (SARS) nucleocapsid and spike protein-based immunoglobulin G immunoassays were developed and evaluated. Our assays demonstrated high sensitivity and specificity to the SARS coronavirus in sera collected from patients as late as 2 years postonset of sympt...

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Auteurs principaux: Haynes, Lia M., Miao, Congrong, Harcourt, Jennifer L., Montgomery, Joel M., Le, Mai Quynh, Dryga, Sergey A., Kamrud, Kurt I., Rivers, Bryan, Babcock, Gregory J., Oliver, Jennifer Betts, Comer, James A., Reynolds, Mary, Uyeki, Timothy M., Bausch, Daniel, Ksiazek, Thomas, Thomas, William, Alterson, Harold, Smith, Jonathan, Ambrosino, Donna M., Anderson, Larry J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Clinical and Diagnostic Laboratory Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828864/
https://ncbi.nlm.nih.gov/pubmed/17229882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00351-06
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