Recombinant Protein-Based Assays for Detection of Antibodies to Severe Acute Respiratory Syndrome Coronavirus Spike and Nucleocapsid Proteins

Recombinant severe acute respiratory syndrome (SARS) nucleocapsid and spike protein-based immunoglobulin G immunoassays were developed and evaluated. Our assays demonstrated high sensitivity and specificity to the SARS coronavirus in sera collected from patients as late as 2 years postonset of sympt...

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Detalhes bibliográficos
Main Authors: Haynes, Lia M., Miao, Congrong, Harcourt, Jennifer L., Montgomery, Joel M., Le, Mai Quynh, Dryga, Sergey A., Kamrud, Kurt I., Rivers, Bryan, Babcock, Gregory J., Oliver, Jennifer Betts, Comer, James A., Reynolds, Mary, Uyeki, Timothy M., Bausch, Daniel, Ksiazek, Thomas, Thomas, William, Alterson, Harold, Smith, Jonathan, Ambrosino, Donna M., Anderson, Larry J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Clinical and Diagnostic Laboratory Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828864/
https://ncbi.nlm.nih.gov/pubmed/17229882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00351-06
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