Transcriptional Regulation by Protein Kinase A in Cryptococcus neoformans

A defect in the PKA1 gene encoding the catalytic subunit of cyclic adenosine 5′-monophosphate (cAMP)–dependent protein kinase A (PKA) is known to reduce capsule size and attenuate virulence in the fungal pathogen Cryptococcus neoformans. Conversely, loss of the PKA regulatory subunit encoded by pkr1...

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Autores principales: Hu, Guanggan, Steen, Barbara R, Lian, Tianshun, Sham, Anita P, Tam, Nicola, Tangen, Kristin L, Kronstad, James W
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828699/
https://ncbi.nlm.nih.gov/pubmed/17367210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030042
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