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Synthesis and activity of a potent, specific azabicyclo [3.3.0] octane-based DPP II inhibitor

A cell permeable DPP II (also known as DPP2, DPP7 and quiescent cell proline dipeptidase (QPP)) inhibitor has been synthesized. The azabicyclo[3.3.0]octane-based inhibitor is potent and selective and elicits very similar quiescent lymphocyte death to previously characterized inhibitors that are not...

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Bibliographische Detailangaben
Hauptverfasser: Danilova, Olga, Li, Bei, Szardenings, Katrin, Huber, Brigitte T., Rosenblum, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828633/
https://ncbi.nlm.nih.gov/pubmed/17055271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.10.012
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