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Interleukin-12 Promotes Gamma Interferon-Dependent Neutrophil Recruitment in the Lung and Improves Protection against Respiratory Streptococcus pneumoniae Infection

The ability of exogenous interleukin-12 (IL-12) to elicit protective innate immune responses against the extracellular pathogen Streptococcus pneumoniae was tested by infecting BALB/c mice intranasally (i.n.) with S. pneumoniae after i.n. administration of IL-12. It was found that administration of...

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Detalhes bibliográficos
Main Authors: Sun, Keer, Salmon, Sharon L., Lotz, Steven A., Metzger, Dennis W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828591/
https://ncbi.nlm.nih.gov/pubmed/17210665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01403-06
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