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In Vitro Induction of Immunoglobulin A (IgA)- and IgM-Secreting Plasma Blasts by Cholera Toxin Depends on T-Cell Help and Is Mediated by CD154 Up-Regulation and Inhibition of Gamma Interferon Synthesis

Cholera toxin (CT) and the type II heat-labile enterotoxins (LT-IIa and LT-IIb) are potent immunological adjuvants which are hypothesized to enhance the production of antibody (Ab)-secreting cells, although their mechanisms of action are not fully understood. The treatment of splenic cells with conc...

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Detalhes bibliográficos
Main Authors: Arce, Sergio, Nawar, Hesham F., Muehlinghaus, Gwendolin, Russell, Michael W., Connell, Terry D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828582/
https://ncbi.nlm.nih.gov/pubmed/17220318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01367-06
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