c-Fos-Deficient Mice Are Susceptible to Salmonella enterica Serovar Typhimurium Infection

c-Fos is a component of transcription factor AP-1. We show that macrophages lacking c-Fos exhibit enhanced production of proinflammatory cytokines, potentiated NF-κB phosphorylation, and increased cell death following Salmonella enterica serovar Typhimurium infection. Furthermore, mice lacking c-Fos...

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Hlavní autoři: Maruyama, Kenta, Sano, Gen-ichiro, Ray, Neelanjan, Takada, Yasunari, Matsuo, Koichi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828558/
https://ncbi.nlm.nih.gov/pubmed/17178788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01316-06
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