Leishmania-Derived Murine Monocyte Chemoattractant Protein 1 Enhances the Recruitment of a Restrictive Population of CC Chemokine Receptor 2-Positive Macrophages

Transgenic Leishmania parasites that encode the murine chemokine monocyte chemoattractant protein 1 (MCP-1) were generated. These parasites transcribed MCP-1 mRNA and secreted MCP-1 protein. Infection of BALB/c, C57BL/6, or MCP-1 knockout (KO) mice with these parasites resulted in minimal lesion dev...

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Detalhes bibliográficos
Main Authors: Conrad, Sean M., Strauss-Ayali, Dalit, Field, Ann E., Mack, Matthias, Mosser, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828528/
https://ncbi.nlm.nih.gov/pubmed/17088347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01314-06
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