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Chlamydia pneumoniae-Induced Macrophage Foam Cell Formation Is Mediated by Toll-Like Receptor 2

Chlamydia pneumoniae induces macrophage foam cell formation, a hallmark of early atherosclerosis, in the presence of low-density lipoprotein (LDL). This study examined the role that Toll-like receptor 2 (TLR2) and TLR4 may play in pathogen-induced foam cell formation. Murine macrophage RAW 264.7 cel...

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Detalhes bibliográficos
Main Authors: Cao, Fei, Castrillo, Antonio, Tontonoz, Peter, Re, Fabio, Byrne, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828523/
https://ncbi.nlm.nih.gov/pubmed/17145941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01386-06
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