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Hypervirulence of a Rough Variant of the Mycobacterium abscessus Type Strain

We isolated a rough variant of Mycobacterium abscessus CIP 104536T during experimental infection of mice. We show that this variant has lost the ability to produce glycopeptidolipids, is hyperlethal for C57BL/6 mice infected intravenously, and induces a strong tumor necrosis factor-alpha response by...

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Bibliografiska uppgifter
Huvudupphovsmän: Catherinot, E., Clarissou, J., Etienne, G., Ripoll, F., Emile, J.-F., Daffé, M., Perronne, C., Soudais, C., Gaillard, J.-L., Rottman, M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828507/
https://ncbi.nlm.nih.gov/pubmed/17145951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00835-06
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