Intranasal Vaccination with a Secreted Chlamydial Protein Enhances Resolution of Genital Chlamydia muridarum Infection, Protects against Oviduct Pathology, and Is Highly Dependent upon Endogenous Gamma Interferon Production

There is currently no licensed vaccine against Chlamydia trachomatis, the leading cause of sexually transmitted bacterial disease worldwide. Conventional vaccination attempts using surface-exposed chlamydial antigens have achieved only partial success. We have employed a novel vaccination strategy u...

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Detalhes bibliográficos
Main Authors: Murthy, Ashlesh K., Chambers, James P., Meier, Patricia A., Zhong, Guangming, Arulanandam, Bernard P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828486/
https://ncbi.nlm.nih.gov/pubmed/17118987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01280-06
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